Description
Product Overview
The Hamilton 79354 PRP‑X100 LC column is engineered for high‑performance liquid chromatography applications where reliable anion separation is essential. Constructed with a Peek (polyether ether ketone) housing, the column offers exceptional chemical resistance, thermal stability, and mechanical strength, ensuring consistent performance even under rigorous cleaning cycles. Its dimensions of 150 × 4.6 mm provide a standard format that fits seamlessly into most laboratory HPLC systems, while the internal packing material is optimized for the separation of the eight most common anions, including fluoride, chloride, bromide, nitrate, nitrite, phosphate, carbonate, and sulfate. The column is supplied by Thomas Scientific, a trusted distributor in the scientific community, and carries the model number 79354, reflecting its place within Hamilton’s extensive portfolio of chromatography solutions.
Usage
Designed for versatility, the Hamilton 79354 column performs exceptionally well in a variety of laboratory environments, from academic research labs to industrial quality‑control facilities. It can be used with purely aqueous mobile phases or with organic solvents ranging from 0 % to 100 % organic content, allowing analysts to tailor elution conditions to the specific chemical properties of the target anions. The column excels in water analysis, environmental monitoring, pharmaceutical impurity profiling, and food safety testing, where accurate quantification of anionic species is critical. Its robust construction also makes it suitable for high‑throughput workflows, where frequent column regeneration and cleaning are required without compromising column integrity or separation efficiency.
Why Choose Us
When selecting a chromatography column, reliability, reproducibility, and support are paramount. Hamilton’s reputation for precision engineering, combined with Thomas Scientific’s dedicated customer service, ensures that you receive a product that meets stringent quality standards and is backed by responsive technical assistance. The Peek material not only resists aggressive solvents but also minimizes background noise, contributing to cleaner chromatograms and more accurate quantitation. Additionally, the column is manufactured under controlled conditions that guarantee batch‑to‑batch consistency, reducing method development time and enhancing method transferability across different instruments and laboratories.
Key Features
- Peek housing provides superior chemical resistance and durability for long‑term use.
- Optimized for separation of eight common anions, delivering clear, reproducible results.
- Compatible with 0‑100 % organic solvents, offering flexibility for diverse mobile phase compositions.
- Standard 150 × 4.6 mm size fits most HPLC systems, simplifying installation and method integration.
- Supported by Thomas Scientific’s expert technical service and comprehensive after‑sales assistance.
FAQ
What types of anions can this column separate?
The Hamilton 79354 column is specifically designed to separate the eight most common anions: fluoride, chloride, bromide, nitrate, nitrite, phosphate, carbonate, and sulfate. This makes it ideal for water quality testing, environmental analysis, and pharmaceutical impurity profiling.
Can the column be used with high percentages of organic solvent?
Yes. The column’s Peek housing tolerates organic solvents from 0 % up to 100 %, allowing you to adjust the mobile phase composition to achieve optimal separation for a wide range of sample matrices.
How often should the column be cleaned or regenerated?
Routine cleaning after each batch of samples is recommended to maintain performance. The column can withstand aggressive cleaning protocols due to its robust construction, extending its usable lifespan and reducing downtime.
Is the column compatible with standard HPLC equipment?
Absolutely. Its 150 × 4.6 mm dimensions are a common format for most HPLC systems, ensuring straightforward installation without the need for additional adapters or modifications.
What support does Thomas Scientific provide for this product?
Thomas Scientific offers comprehensive technical support, including method development assistance, troubleshooting guidance, and warranty coverage. Their knowledgeable staff can help you optimize your chromatography conditions and resolve any issues that may arise during use.




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