Silica Gel 60 Adsorbents for LC Chromatography – MACHEREY-NAGEL 1 kg

Description

Product Overview

MACHEREY-NAGEL Silica Gel 60 is a premium-grade adsorbent specifically engineered for liquid chromatography (LC) column packing. The material features a well‑defined pore size of approximately 60 Å, which provides optimal surface area for interaction with a wide range of analytes. Particle dimensions range from 0.063 to 0.2 mm, delivering a balance between mechanical stability and high efficiency. The bulk packaging of 1 kg ensures sufficient supply for both small‑scale method development and large‑scale production runs. Manufactured under strict quality‑control protocols, this silica gel meets the rigorous standards required for reproducible chromatographic performance.

Usage

This silica gel is intended for use in a variety of LC applications, including analytical, semi‑preparative, and preparative columns. It excels in reversed‑phase, normal‑phase, and mixed‑mode separations, making it a versatile choice for pharmaceutical, environmental, and biochemical laboratories. The material is compatible with common mobile phases such as water, acetonitrile, methanol, and various buffer systems. Users typically suspend the silica in a slurry solvent, pack the column under controlled pressure, and then condition the column before sample injection. Its consistent particle size distribution minimizes channeling and reduces back‑pressure, which is essential for high‑throughput workflows.

Why Choose Us

Choosing MACHEREY-NAGEL means selecting a brand with decades of experience in chromatography media development. Our Silica Gel 60 is produced using high‑purity raw materials, resulting in low metal ion leaching and minimal background absorbance. The product undergoes comprehensive testing for particle size uniformity, pore volume consistency, and chemical stability, guaranteeing that each batch performs identically. In addition, our customer support team provides technical assistance for method optimization, column packing protocols, and troubleshooting, ensuring that you achieve the best possible results from day one.

Key Features

• Uniform 0.063‑0.2 mm particle size for smooth column packing and low back‑pressure.
• Consistent 60 Å pore diameter delivers high resolution and reproducible separations.
• High‑purity silica minimizes background noise and metal ion contamination.
• Suitable for a wide range of LC modes, including reversed‑phase and normal‑phase.
• Dedicated technical support and method‑development assistance from experienced chemists.

FAQ

What particle size range is suitable for analytical LC columns?

For analytical columns, the 0.063‑0.2 mm range provides excellent efficiency while maintaining manageable back‑pressure. Smaller particles (around 0.063 mm) are ideal for high‑resolution separations, whereas the larger end of the range (0.2 mm) offers lower pressure for longer columns.

Can this silica gel be used for normal‑phase chromatography?

Yes. The silica surface is chemically inert and can be functionalized or used directly for normal‑phase separations, making it a flexible choice for a variety of polarity‑based methods.

How do I reduce column back‑pressure when packing with this material?

Ensuring a well‑dispersed slurry, using appropriate packing pressure, and selecting the larger particle size within the specified range can help lower back‑pressure without sacrificing performance.

Is the product compatible with acidic mobile phases?

MACHEREY‑NAGEL Silica Gel 60 is stable under a wide pH range, including acidic conditions down to pH 2, making it suitable for many acid‑based mobile phases.

What warranty or guarantee does MACHEREY‑NAGEL provide?

We offer a quality guarantee that the product will meet the specifications listed. If any performance issues arise due to material defects, our support team will work with you to resolve the problem, including replacement or technical guidance.